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目的对原发性干燥综合征患者的临床表现进行分析,以期提高原发性干燥综合征诊疗水平。方法对平顶山神马医院2011年1月—2013年12月收治的78例原发性干燥综合征患者皮肤黏膜表现和免疫学检查进行回顾性分析。结果原发性干燥综合征患者主要的皮肤黏膜表现有紫癜、皮肤干燥、口腔溃疡、雷诺现象、红斑结节等,发生率占所有患者39.74%,皮肤干燥、紫癜、口腔溃疡、红斑结节等发生率大于10%。原发性干燥综合征患者皮肤黏膜表现正常和异常组之间在其他常见症状和免疫学检查方面无显著性差异(P>0.05)。结论原发性干燥综合征患者诊断,应当密切注意皮肤黏膜表现,提高诊断和治疗原发性干燥综合征水平。
Objective To analyze the clinical manifestations of patients with Sjogren’s syndrome in order to improve the diagnosis and treatment of Sjogren’s syndrome. Methods A retrospective analysis was performed on skin mucosal manifestations and immunological tests in 78 patients with Sjogren’s syndrome admitted to Pingdingshan Shenma Hospital from January 2011 to December 2013. Results The main mucocutaneous manifestations of patients with primary Sjögren’s syndrome were purpura, dry skin, oral ulcers, Raynaud’s phenomenon, erythema nodules, etc. The incidence rate was 39.74% in all patients with dry skin, purpura, oral ulcers and erythema nodules The incidence is greater than 10%. There was no significant difference in other common symptoms and immunological tests between normal and abnormal skin mucosa in patients with Sjogren’s syndrome (P> 0.05). Conclusion The diagnosis of patients with Sjogren’s syndrome should pay close attention to the performance of the skin and mucosa, improve the diagnosis and treatment of Sjogren’s syndrome.