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目的探讨甲状腺动脉栓塞治疗难治性G raves病的临床应用。方法30例难治性G raves病患者经超选择插管至甲状腺上、下动脉造影,根据动脉管径选择不同直径的聚乙烯醇分步栓塞,并用钢圈加强。栓塞体积达80%以上。结果30例患者栓塞术均成功。栓塞2周后,临床症状消失,甲状腺体积缩小,4周后甲状腺功能正常。随访24~40个月,26例临床治愈,无甲状腺功能减低或甲状旁腺功能减低,突眼无加重。4例复发,其中3例服抗甲状腺药物治疗,1例手术治疗。结论介入栓塞甲状腺上、下动脉治疗难治性G raves病简单、安全、疗效显著,为G raves病的治疗提供了一种有效的新方法。
Objective To investigate the clinical application of thyroid artery embolization in the treatment of refractory G raves disease. Methods Thirty patients with refractory G raves disease underwent superselective intubation to the superior and inferior thyroid gland. According to the arterial diameter, polyvinyl alcohol of different diameters were divided into two groups to be embolized and reinforced with steel rings. Embolism volume of 80% or more. Results Thirty patients had successful embolization. Two weeks after embolization, clinical symptoms disappeared, the thyroid volume was reduced, and thyroid function was normal after 4 weeks. Follow-up 24 to 40 months, 26 cases of clinical cure, no reduction of thyroid function or hypoparathyroidism, exophthalmos no aggravation. 4 cases relapsed, of which 3 cases of anti-thyroid drug treatment, 1 case of surgical treatment. Conclusions The interventional embolization of the superior and inferior thyroid arteries in the treatment of refractory G raves is a simple, safe and effective method and provides a new and effective method for the treatment of G raves disease.