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碘酊是医院最常用的消毒防腐药之一。在我国,虽然配制碘酊已经有较长的历史了,但是目前还没有比较统一的适合医院制剂室的配制方法。笔者最近查阅了1981年以后出版的包括中国药典在内的十几本收载碘酊配制方法的书及部分省、市的制剂手册(制剂规范),很少有完全相同的配制方法。这些配制方法的主要不同之处,一是溶解碘化钾时加水量不同,二是加入乙醇的时间不同。虽然按这些方法都能配制出合格的碘酊,但配制时碘和碘化钾的溶解速度是有差别的,对碘酊质量有一定的影响。
Iodine tincture is one of the most commonly used antiseptic agents in hospitals. In our country, although the preparation of iodine tincture has a long history, but at present there is no more uniform method for the preparation of hospital preparation room. The author recently reviewed the books published since 1981, including the Chinese Pharmacopoeia more than a dozen books containing the preparation method of iodine and some provincial and municipal manuals (preparation specifications), there are seldom exactly the same formulating method. The main difference between these preparation methods, one is the dissolution of potassium iodide different amount of water, the second is the time of adding ethanol is different. Although these methods can be prepared out of qualified iodine tincture, but the preparation of iodine and potassium iodide dissolution rate is different, the quality of iodine tin has a certain impact.