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目的:研究高风险初产妇妊娠期糖尿病(GDM)的筛查对妊娠结局和新生儿的影响。方法:选取2011年1月~2014年2月期间来该院进行产前检查并建档的300例高风险的初产妇作为研究对象,均在妊娠24~28周接受50 g葡萄糖负荷试验(GCT)和75 g葡萄糖耐量试验(OGTT),并定期复查血糖。根据血糖水平将300例产妇分为观察组231例和对照组69例,比较两组产妇的剖宫产率、不良反应和并发症的发生率;比较两组新生儿的1 min和5 min Apgar评分;比较两组围产儿的并发症发生率。结果:观察组产妇的剖宫产率9.96%,不良反应发生率4.76%,并发症发生率4.33%;对照组产妇剖宫产率24.64%,不良反应发生率13.04%,并发症发生率15.94%,两组比较差异具有统计学意义(P<0.05)。观察组新生儿1 min Apgar评分(9.5±0.2)分,围产儿并发症发生率4.33%;对照组新生儿1 min Apgar评分(9.0±0.3)分,围产儿并发症发生率14.71%,两组比较差异具有统计学意义(P<0.05)。两组新生儿的5 min Apgar评分差异无统计学意义(P>0.05)。结论:高风险产妇GDM的筛查对改善妊娠结局和新生儿的预后意义重大。
PURPOSE: To study the effects of screening for gestational diabetes mellitus (GDM) in high-risk first-mover women on pregnancy outcomes and neonates. Methods: A total of 300 high-risk primipara from January 2011 to February 2014 were enrolled in this hospital. All 50 high-risk primipara patients were enrolled in this study. All pregnant women received 50 g glucose load test (GCT ) And 75 g glucose tolerance test (OGTT), and regular review of blood glucose. According to the blood glucose level, 300 women were divided into observation group (231 cases) and control group (69 cases). The incidences of cesarean section, adverse reactions and complication rates were compared between two groups. Apgar Score; compare the incidence of complications of two groups of perinatal. Results: The rate of cesarean section, the incidence of adverse reactions and the incidence of complications in observation group were 9.96%, 4.76% and 4.33% respectively. The incidence of cesarean section in control group was 24.64%, the incidence of adverse reactions was 13.04% and the incidence of complications was 15.94% , The difference between the two groups was statistically significant (P <0.05). The Apgar score (9.5 ± 0.2) at 1 min and the incidence of perinatal complications in observation group were 4.33% at 1 min. The Apgar score at 1 min was 9.0 ± 0.3 in control group, and the incidence of perinatal complications was 14.71% The difference was statistically significant (P <0.05). There was no significant difference in 5 min Apgar score between two groups (P> 0.05). Conclusion: Screening high-risk maternal GDM is of great importance for improving pregnancy outcomes and the prognosis of newborns.