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必须假定儿童急性骨髓炎是由产生青霉素酶的葡萄球菌引起,直至确诊。开始治疗时应给抗青霉素酶的青霉素,或先锋霉素。为使抗菌素进入骨内失去血管的坏死区域,需要提高血内抗菌素的浓度。因此一般需胃肠道外给抗菌素而住院4—6周。作者治疗14名急性金黄色葡萄球菌性(血浆凝固酶阳性)骨髓炎患儿。入院开始给静注或肌注先锋霉素Ⅱ。前7例患儿是100毫克/公斤/天,后7例是200毫克/公斤/天,分6次注射。仅1例在入院当天切开引流。一旦局部或用身炎症征象消失,即
It must be assumed that acute osteomyelitis in children is caused by penicillinase-producing staphylococci until confirmed. Penicillin should be given to penicillin, or cephalosporins when starting treatment. In order to make the antibiotic enter the necrotic area of the bone and lose the blood vessel, it is necessary to raise the intra-blood antibiotic concentration. Therefore, the general need for antibiotics outside the gastrointestinal tract for 4-6 weeks. The authors treated 14 children with acute Staphylococcus aureus (plasma coagulase-positive) osteomyelitis. Admitted to intravenous or intravenous injection of cephalosporin II. The first seven cases were 100 mg / kg / day and the last 7 were 200 mg / kg / day in 6 injections. Only one patient underwent drainage on the day of admission. Once the signs of local or systemic inflammation disappear, that is