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局部用匹罗卡品治疗眼压升高已有一百多年的历史。但因每天需用药4次,使其应用受限制和不易使病人接受。近来匹罗卡品制成高粘稠度的凝胶以延长该药与泪膜接触时间。本文一眼用4%匹罗卡品凝胶,就寝时给一次;另一眼滴用4%匹罗卡品溶液每天4次,对比缩瞳和降压的效果。参加本治疗组的15例病人,近期未曾做过眼手术,无炎症,无眼睑显著异常,全身亦未用影响眼压的药物。实验前48小时停用匹罗卡品,30天前停用肾上腺素。第一天在早8、12、下午4及10点测量眼压和瞳孔直径。此后一眼在早7、12点半、晚6及
Topical piroctone treatment of intraocular pressure has been a hundred years of history. However, 4 times a day because of medication, its application is limited and not easy for patients to accept. Recently, pilocarpine has been made into highly viscous gels to prolong the contact time between the drug and the tear film. This article with a 4% pilocarpine gel, go to bed once; the other eye drops with 4% pilocarpine solution 4 times a day, compared to the effect of miosis and blood pressure. 15 patients participated in the treatment group, have not done any surgery recently, no inflammation, no significant eyelid abnormalities, the body also did not affect the use of intraocular pressure drugs. Pilocarpine was discontinued 48 hours prior to the experiment and epinephrine was discontinued 30 days earlier. On the first day, IOP and pupil diameter were measured at 8, 12 and 4 o’clock in the afternoon. After a look in the morning 7,12 half past six and later