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目的探讨血浆灌流方法在急性妊娠脂肪肝治疗中的疗效。方法将郑州大学第一附属医院2007年6月—2013年6月收治的54例妊娠急性脂肪肝住院患者分为2组,对照组(39例)予内科保守治疗,治疗组(15例)在内科保守治疗的同时应用PP方法。治疗2周后,观察患者的症状、体征、生化指标治疗前后是否有显著差异性。结果①治疗组患者的谷草转氨酶、谷丙转氨酶与对照组比较差异有显著性意义(P<0.05)。②治疗组治疗前后各项化验指标比治疗前疗效有明显差异性(P<0.05)。结论 PP法治疗急性妊娠脂肪肝安全有效,早期连续应用可以有效的延缓病情进展。
Objective To investigate the efficacy of plasma perfusion in the treatment of acute pregnancy fatty liver. Methods 54 cases of acute fatty liver disease inpatients admitted to the First Affiliated Hospital of Zhengzhou University from June 2007 to June 2013 were divided into two groups. The control group (39 cases) received conservative treatment of internal medicine. The treatment group (15 cases) Conservative treatment of internal medicine with PP method. After 2 weeks of treatment, observe the patients’ symptoms, signs and biochemical indexes before and after treatment whether there is significant difference. Results ① Aspartate aminotransferase and alanine aminotransferase in the treatment group were significantly different from those in the control group (P <0.05). ② The treatment group before and after treatment of various indicators than before treatment curative effect was significantly different (P <0.05). Conclusion PP treatment of acute fatty liver of pregnancy is safe and effective, early continuous application can effectively delay the progression of the disease.