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为观察尼莫地平对妊高征患者视网膜中央动脉血流的影响,在14例妊高征患者口服尼莫地平前后用彩色多普勒检测视网膜中央动脉血流,并与同用14例静滴硫酸镁者比较。结果显示尼莫地平显著降低视网膜中央动脉搏动指数(PI)(P<0.01),同时明显降低血压(P<0.05)。尼莫地平扩张视网膜中央动脉,提示其对脑部其它小动脉有相似作用。故尼莫地平可能成为今后妊高征治疗的另一种选择。
To observe the effect of nimodipine on central retinal artery blood flow in PIH patients, central retinal artery blood flow was detected by color Doppler before and after oral administration of nimodipine in 14 patients with PIH. Comparison of magnesium sulfate. The results showed that nimodipine significantly reduced the central retinal artery pulsatility index (PI) (P <0.01), while significantly lower blood pressure (P <0.05). Nimodipine dilates the central retinal artery, suggesting that it has similar effects on other small arteries in the brain. Therefore, nimodipine may become the future treatment of pregnancy induced hypertension Another option.