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目的:观察小儿手足口病应用阿昔洛韦进行治疗的临床效果。方法:收集我院就诊的148例小儿手足口病患者的资料,随机平均分组,分别对患儿实施阿昔洛韦和利巴韦林静脉滴注治疗,观察患儿临床体征的变化,对疗效作出评价。结果:实验组使用阿昔洛韦疗效确切,总有效率为95.95%,明显高于使用利巴韦林的对照组85.14%(P<0.05),实验组疱疹消退的平均时间也显著短于对照组(P<0.05)。结论:阿昔洛韦治疗小儿手足口病疗效较好,起效快,无副作用,可在临床上广泛应用。
Objective: To observe the clinical effect of acyclovir in children with HFMD. Methods: The data of 148 cases of HFMD in our hospital were collected and randomly divided into groups. The patients were treated with intravenous infusion of acyclovir and ribavirin respectively. The changes of clinical signs in children were observed. Make a comment Results: The efficacy of acyclovir in experimental group was 95.95%, significantly higher than 85.14% (P <0.05) in control group using ribavirin. The mean time to herpes regression in experimental group was also significantly shorter than that in control group Group (P <0.05). Conclusion: Aciclovir is effective in treating hand-foot-mouth disease in children with rapid onset and no side effects. It can be widely used clinically.