论文部分内容阅读
目的:探讨弥散张量纤维束成像(diffusion tensor tractography,DTT)其在脑肿瘤中的应用价值。方法:对83例脑肿瘤行常规MRI及DTT检查,通过获取部分各向异性图(FA图)、彩色编码张量图及脑白质纤维束图,依次分析83患者肿瘤与瘤周白质纤维束之间的关系。测量83脑肿瘤患者肿瘤实质区、瘤周水肿区、邻近白质区及对侧正常白质区的ADC值、FA值。结果:ADC值在肿瘤实质区,瘤周水肿区,邻近白质区中,低级别胶质瘤与高级别胶质瘤具有差异性,而在正常白质区差异不具有统计学意;FA值在肿瘤实质区,低级别胶质瘤与高级别胶质瘤具有差异性,而在瘤周水肿区,邻近白质区中,正常白质区差异不具有统计学意义。且83例良、恶性肿瘤瘤周白质纤维束都可以发生移位;瘤周水肿区白质纤维束表现为浸润和破坏为主,其破坏程度与肿瘤的恶性程度呈正比。结论:DTT可直观显示脑白质损伤程度并观察神经纤维束受损范围。
Objective: To investigate the value of diffusion tensor tractography (DTT) in brain tumors. Methods: Eighty-three patients with brain tumors underwent routine MRI and DTT examinations. By acquiring partial anisotropy (FA) images, color-coded tensorograms and white matter fiber bundles, 83 patients with tumor and peritumoral white matter fiber bundles Relationship between. The ADC value and FA value were measured in the tumor parenchyma, peritumoral edema area, adjacent white matter area and the contralateral normal white matter of 83 brain tumor patients. Results: There was a significant difference between low grade gliomas and high grade gliomas in the tumor parenchyma, peritumoral edema and adjacent white matter, but not in the normal white matter In the parenchyma, low-grade glioma and high-grade glioma are different, while in the peritumoral edema area, the adjacent white matter area, the normal white matter difference was not statistically significant. 83 cases of benign and malignant tumors around the white matter fiber bundles can shift; peritumoral edema white matter fiber bundles showed infiltration and destruction of the main, the extent of the damage is proportional to the degree of malignancy of the tumor. Conclusion: DTT can directly show the degree of white matter damage and observe the scope of nerve fiber bundle damage.