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目的 :观察羟基脲联合干扰素治疗真性红细胞增多症的疗效。方法 :41例患者为治疗组 ,应用羟基脲联合干扰素治疗 ,选择单用羟基脲治疗患者 3 8例作为对照组 ,观察治疗前后外周血红细胞、白细胞、血小板变化剂治疗组与对照组的疗效。结果 :治疗组治疗后外周血白细胞、红细胞、血红蛋白、血小板均下降 ,较治疗前有明显差异 (P <0 0 5 )。治疗后较对照组下降明显 ,二者有显著性差异 (P <0 0 5 )结论 :羟基脲联合干扰素治疗真性红细胞增多症疗效较单用羟基脲好。
Objective: To observe the efficacy of hydroxyurea combined with interferon in the treatment of polycythemia vera. Methods: Forty-one patients were treated with hydroxyurea combined with interferon. 38 patients treated with hydroxyurea alone were selected as the control group. The therapeutic effects of peripheral blood red blood cells, white blood cells, platelet-activating agents and the control group were observed before and after treatment . Results: After treatment, the number of leucocytes, erythrocytes, hemoglobin and platelets in the treatment group decreased significantly compared with that before treatment (P <0.05). After treatment, compared with the control group decreased significantly, the two were significantly different (P <0 05) Conclusion: hydroxyurea combined with interferon treatment of polycythemia vera is better than single hydroxyurea good.