Tamoxifen Induces Apoptosis of Mouse Microglia Cell Line BV-2 Cells via both Mitochondrial and Death

• 作 者: 李正伟 陈劲草 雷霆 张华楸
• 机 构: DepartmentofNeurosurgery
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2012年2期
• 关键词: MICROGLIA BV- CELLS APOPTOSIS TAMOXIFEN MITOCHONDRIA death receptor microglia B

Little is known about whether tamoxifen (TAM) can affect resting state microglia apoptosis and about the cellular mechanism that may account for this. To explore this question, we incubated the microglia cell line BV-2 cells with TAM at different concentr