TUMORIGENESIS相关论文
人类微小RNA（microRNA,简称miRNA）通过和Ago2蛋白结合形成RISC复合物（RNA-induced silencing complex）,介导mRNA降解和抑制mRNA翻译,发......
Insights into the Pathogenesis of Preeclampsia Based on the Features of Placentation and Tumorigenes
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核转录因子红细胞系-2p45 （NF-E2）相关因子-2 (nuclear factor erythroid-2p45-related factor2，Nrf2)介导的细胞适应性氧化应激反应......
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肿瘤发生是一个多步骤过程.绝大多数人肿瘤由产生了系列相继变化的单一细胞形成.这些变化导致细胞有丝分裂信号或生长控制的细微异......
CTNNB1 (or beta-catenin) is regarded as a central effecter in molecules of the wingless/Wnt signalling pathway. It is a ......
miRNAs are a class of small, ~22nt, non-coding RNAs that negatively regulate gene expression at the post- transcriptiona......
Reactive oxygen species (ROS) are molecules or ions formed by the incomplete one-electron reduction of oxygen. Ofinteres......
Appropriately controlled gene expression is fundamental for normal growth and survival of all living organisms.In eukary......
A major portion of the mammalian genome is transcribed to produce large numbers of noncoding RNAs(ncRNAs).During the pas......
The link between chronic inflammation and colorectal cancer has been well established. The events proceeding along tumor......
Recently,the research group led by Prof.Wu Mian and Pro~Mei Yide from University of Science and Technology of China has ......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的 研究高迁移率蛋白A2(HMGA2)和血管内皮生长因子(VEGF)在膀胱尿路上皮癌中发生及复发中的表达及其意义.方法应用免疫组织化学......
目的探讨三磷酸腺苷酶家族蛋白2（ATAD2）在不同病变肝组织中的表达情况及其临床应用价值。方法用免疫组织化学法检测ATAD2在60例肝细......
Background Very recent studies revealed that obstructive sleep apnoea (OSA) is a contributor of the increased incidence ......
Objective:Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans.It has always bee......
The genome of cells is constantly challenged by DNA damages from endogenous metabolism and environmental agents. These d......
胃癌是恶性肿瘤中造成癌症相关死亡的主要原因之一，其发病机制、化疗耐药、早期诊断及预后判断等诸多问题的研究尚不明确。长非编码......
Studies over the past decades have uncovered fusion genes, a class of oncogenes that provide immense diagnostic and ther......
Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and dru
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Low-density lipoprotein receptor-related protein 1(LRP1,also known as CD91),a multifunctional endocytic and cell signali......
Synergistic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and N-nitrosodiethylamine tion Cell Malig
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
表观遗传指不改变DNA序列的基因表达改变,是多细胞真核生物的重要生物学现象.在个体发生过程中,干细胞一旦分化为某种分化细胞,该......
随着肿瘤干细胞(CSC)假说的出现,肿瘤研究领域经历了一次革命,人们从新的角度认识和研究肿瘤.面对肿瘤难以根治这一难题,CSC理论带......
SM22α是一种重要的细胞骨架相关蛋白,近年来发现它在细胞转化、分裂、黏附、转移中都发挥了重要作用.研究表明它在乳腺癌、大肠癌......
对肝癌组织和肝硬化组织进行抑制性消减杂交在肝癌中获得的高表达基因P02,它与TPT1基因高度同源,认为P02即TPT1.研究结果表明阻断......
Nonmetabolic functions of pyruvate kinase isoform M2 in controlling cell cycle progression and tumor
Pyruvate kinase catalyzes the rate-limiting final step of glycolysis,generating adenosine triphosphate (ATP) and pyruvat......
肿瘤的发生发展是一个涉及多基因改变、多信号通路的过程。 GRIM-19是一个新的细胞凋亡调控基因，其基因的突变、蛋白表达的缺失发生......
目的 探讨灰黄霉素在体内外对人前列腺癌PC-3细胞抗肿瘤作用的可能机制.方法 不同浓度(0、5、10、15、20、25 μg/ml)的灰黄霉素作......
目的 观察胃癌相关蛋白质POSTN在胃黏膜癌变过程中的表达与意义,为胃癌的早期诊断、病理分型与评估预后提供有价值的实验依据.方法......
Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and dru
The FOXO3a and FOXM1 forkhead transcription factors are key players in cancer initiation, progression, and drug resistan......
A novel human gene spindlin1,encoding a protein localized in the cell nucleus and inducing NIH3T3 ce
A novel human gene, spindlin1, recently cloned in our laboratory, is highly expressed in the tissue of ovary cancer. To ......
Objective We examined alterations in the expression of tumorigenesis-related genes in the pituitary gland of rats expose......
AIM:To investigate alternative or subordinate pathways involved in colorectal tumorigenesis and tumor growth,possibly de......
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate......
Although we have made great progress in understanding tumor pathogenesis through studies on gene mutation and cancer ste......
Histone deacetylases (HDACs) play an important role in tumorigenesis. Inhibition of HDACs is considered as a potent stra......
Objective To review the leading roles of glioma stem cells (GSCs) and their sophisticated interactions with other cells ......
