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目的:探讨腹腔镜联合促性腺激素激动剂(GnRH-a)对卵巢囊肿剥除术后患者激素分泌水平的影响。方法:选择85例卵巢囊肿患者分为实验组(腹腔镜联合达菲林组)43例,对照组(单纯腹腔镜组)42例,比较两组患者术后血清卵泡剌激素(FSH)、黄体生成素(LH)及雌二醇(E2)的水平,比较两组患者的月经恢复情况、慢性盆腔痛缓解情况、复发情况及妊娠情况。结果:1年复发率两组患者差异有统计学意义(P<0.05),两组患者术后6个月与术前FSH、LH、E2的差异有统计学意义(P<0.05),术后1年实验组LH与术前差异有统计学意义(P<0.05)。结论:腹腔镜联合GnRH-a与单纯腹腔镜治疗卵巢子宫内膜异位囊肿在远期疗效上差异不明显,但近期、特别是1年内两种治疗方式差异有统计学意义,对于有生育要求的患者宜选用腹腔镜联合GnRH-a治疗。
Objective: To investigate the effect of laparoscopic combined with gonadotrophin agonist (GnRH-a) on the hormone secretion in patients with ovarian cyst after ablation. Methods: Eighty-five patients with ovarian cysts were divided into experimental group (Laparoscopic combined with Tamiflu group) and control group (Laparoscopic group) with 42 cases. Serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) levels were compared between the two groups, menstruation recovery, chronic pelvic pain relief, recurrence and pregnancy status. Results: The recurrence rate at 1 year was significantly different between the two groups (P <0.05). There was a significant difference between preoperative FSH, LH and E2 6 months postoperatively in both groups (P 0.05) One year experimental group LH and preoperative difference was statistically significant (P <0.05). Conclusion: Laparoscopy combined with GnRH-a and laparoscopic treatment of ovarian endometriotic cysts in the long-term efficacy of the difference was not significant, but the recent, especially within a year of two kinds of treatment was statistically significant differences in fertility requirements Of patients should use laparoscopic combined with GnRH-a treatment.