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为了探讨牙源性角化囊肿(OKC)中基底细胞的增殖活性和角化类型与预后的关系，本研究通过临床资料分析及银染技术和免疫组织化学技术对22例OKC细胞核仁组成区嗜银蛋白(AgNOR)和细胞核增殖抗原(PCNA)进行了定性、定量研究。结果发现在不全角化OKC中AgNOR阳性颗粒数明显多于正角化者，PCNA能较好地反映细胞增殖活性。并推论OKC的角化类型与预后有密切关系。
In order to investigate the relationship between basal cell proliferation activity and keratinization type and prognosis in odontogenic keratocysts (OKC), the clinical data analysis, silver staining and immunohistochemical techniques were used to detect the nucleolus of OKC cells AgNOR and PCNA were studied qualitatively and quantitatively. The results showed that the number of AgNOR-positive particles in non-full-keratinized OKC was significantly higher than those in positive keratosis, and PCNA could better reflect the cell proliferative activity. And corollary OKC keratosis type and prognosis are closely related.