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目的研究差不嘎蒿的化学成分。方法利用硅胶柱色谱、葡聚糖凝胶等方法对差不嘎蒿的化学成分进行分离纯化,根据其理化性质和波谱数据鉴定化合物的结构。结果从差不嘎蒿中分离得到10个化合物,分别为5-羟基-7,4’-二甲氧基二氢黄酮(5-hydroxy-7,4’-dimethoxyflavanone,1)、3,5-二羟基-7,4’-二甲氧基二氢黄酮(3,5-dihydroxy-7,4’-dimethoxyflavanone,2)、异野樱素(isosakuranetin,3)、7-羟基-5,6-二甲氧基香豆素(umckalin,4)、5,7-二羟基-3,3’,4’-三甲氧基黄酮(5,7-dihydroxy-3,3’,4’-trimethoxyflavone,5)、5-羟基-6,7-二甲氧基香豆素(tomentin,6)、山奈酚-4’-O-甲醚(Kaempferol-4’-O-methylether,7)、泽兰黄素(eupatrin,8)、β-谷甾醇(β-sitosterol,9)、二氢槲皮素-4’-甲醚(taxifolin-4’-methylether,10)。结论化合物4、5、7、8、10为首次从该属植物中分离得到。
Objective To study the chemical constituents of Artemisia chinensis. Methods The constituents of Artemisia halodendron were separated and purified by silica gel column chromatography and Sephadex G-30 gel electrophoresis. The structures of the compounds were identified by their physicochemical properties and spectral data. Results Ten compounds were isolated from Artemisia chinensis, which were 5-hydroxy-7,4’-dimethoxyflavanone (1), 3,5- Dihydroxy-7,4’-dimethoxyflavanone (2), isosakuranetin (3), 7-hydroxy-5,6 Umckalin (4), 5,7-dihydroxy-3,3 ’, 4’-trimethoxyflavone (5,7-dihydroxy- ), 5-hydroxy-6,7-dimethoxycoumarin (6), Kaempferol-4’-O-methylether (7) (eupatrin, 8), β-sitosterol (9) and taxifolin-4’-methylether (10). Conclusion Compounds 4, 5, 7, 8 and 10 were isolated from this genus for the first time.