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1952年Levine和Lown首先提出论据,严肃地批判了急性心肌梗塞必须长期卧床休息与住院治疗的观点。他们的研究证明梗塞后2～7天能够从卧床休息过渡到坐着休息,且在四周内出院,其病死率与并发症发生率无明显增加。1969年Lown和Sidel指出他们观察的病人中,梗塞后第一周未发生并发症的,在第10天或第12天仍住院的无特别优点。
In 1952 Levine and Lown first put forward arguments that seriously criticized the need for long-term bed rest and hospitalization for acute myocardial infarction. Their study showed that 2 to 7 days after infarction, the transition from bed rest to sitting and resting, and within four weeks of discharge, the mortality and complications did not increase significantly. In 1969 Lown and Sidel pointed out that in their observation patients, there was no particular advantage of being hospitalized on day 10 or day 12 with no complications in the first week after infarction.