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柴朴汤临床主要用于过敏性疾病如支气管哮喘,其疗效越来越受到重视。白苏作为其组成药物之一,被认为是其抗过敏作用的有效组分。体内研究显示腹腔注射白苏煎剂抑制小鼠特异抗原IgE的产生、大鼠腹膜肥大细胞组胺的释放,诱导小鼠Th1型细胞因子,提示白苏具有抗过敏作用。但口服给药是否具有抗过敏作用并未完全被证实。曾从白苏中提取出4种酚类成分木犀草素7-O-[β-葡糖醛酸基(2→1)β-
Chai Pu Tang’s clinical application is mainly used for allergic diseases such as bronchial asthma, and its efficacy has been increasingly valued. As one of its constituent drugs, Perilla is considered to be an effective component of its antiallergic action. In vivo studies showed that intraperitoneal injection of Bai Su decoction inhibited the production of mouse specific antigen IgE, histamine release from rat peritoneal mast cells, and induced Th1 cytokines in mice, suggesting that Baisu has anti-allergic effects. However, whether oral administration has anti-allergic effects has not been completely confirmed. Four kinds of phenolic components, luteolin 7-O-[β-glucuronosyl (2→1)β-