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作者报告20例儿童原发性肝癌(PHC),全部由组织学检查确诊。其中男性12例,女性8例。年龄最小者8个月,9～10岁5例,11～16岁14例。1例病人血清甲胎蛋白(AFP)阳性(琼脂扩散法),在其余19例中,18例 AFP>400ng/ml(RIA 法)。其中7例AFP 水平高达1×10~6/ml 以上。所有病人乙肝表面抗原(HBsAg)均阳性(RPH 或 RIA 法)。组织学检查显示19例为梁索型肝癌,1例为假腺体型肝癌。8例作非肿瘤部位肝组织检查,其中6例呈慢性活动性肝炎和肝硬化改变,2例呈慢性迁延型肝炎改变。
The authors report 20 children with primary liver cancer (PHC), all confirmed by histological examination. Including 12 males and 8 females. The youngest of 8 months, 9 to 10 years in 5 cases, 11 to 16 years in 14 cases. One patient was positive for serum alpha-fetoprotein (AFP) (agar diffusion method) and 18 of the remaining 19 patients had AFP> 400 ng / mL (RIA). Seven cases of AFP levels up to 1 × 10 ~ 6 / ml or more. All patients with positive hepatitis B surface antigen (HBsAg) (RPH or RIA method). Histological examination showed that 19 cases of carotid liver cancer, and 1 case of pseudocapillary liver cancer. 8 cases of non-tumor site liver tissue examination, of which 6 cases of chronic active hepatitis and cirrhosis, 2 cases of chronic persistent hepatitis change.