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目的探讨危重新生儿甲状腺激素变化的临床意义。方法以ＩＥＭＬ法测定１６例危重新生儿和２０例正常新生儿的血清Ｔ３、Ｔ４、ＴＳＨ。结果危重新生儿与对照组比较：Ｔ３、Ｔ４明显降低（Ｐ＜００１），ＴＳＨ轻度增高（Ｐ＜００５）。结论危重新生儿也存在正常甲状腺病态综合征，监测危重新生儿的甲状腺激素变化，对判断病情及评价预后具有一定的临床意义。
Objective To investigate the clinical significance of thyroid hormone in critically ill neonates. Methods Serum T3, T4 and TSH were measured by IEML in 16 critically ill newborns and 20 normal newborns. Results Compared with the control group, the levels of T3 and T4 were significantly lower (P <001) and TSH was slightly higher (P <005). Conclusions There are also normal thyroid syndromes in critically ill newborns. Monitoring changes of thyroid hormones in critically ill newborns has some clinical significance in judging the disease and evaluating prognosis.