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单纯疱疹病毒,(HSV)在生物学及流行病学上可分为二种不同类型即HSV_1和HSV_2型。二者均由密切接触传播。前者原发感染在非生殖器部位,而后者通常在生殖器由性交传播。许多疾病归因于HSV感染,这些感染大多是良性的,其中最常见(20％～40％)的是口唇单纯疱疹。但由HSV感染所致的成人肝炎则较少见。自1969年以来,据文献报道在成人中只有21例。除1例外余均死亡。本文报道2例成人单纯疱疹性肝炎,并结合文献报道的病例,总共23例,对本病的临床,和实验室检查特征,作一综述。此外,并对应用免疫过氧化酶方法显示组织中HSV抗原作一描述。
Herpes simplex virus (HSV) can be divided into two different types, HSV_1 and HSV_2, in biology and epidemiology. Both are spread by close contact. The former is primarily infected in the non-genital area, while the latter is usually sexually transmitted in the genitals. Many diseases are due to HSV infection, most of these infections are benign, the most common of which (20% to 40%) is herpes simplex on the lips. However, adult hepatitis due to HSV infection is less common. Since 1969, it has been reported in the literature that there are only 21 cases in adults. All but one died. This article reports 2 cases of herpes simplex hepatitis in adults, and combined with the literature reported cases, a total of 23 cases, the clinical and laboratory features of the disease are reviewed. In addition, the use of immunoperoxidase method shows the organization of HSV antigen as a description.