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细胞角蛋白(Cytokeratin)和癌胚抗原(Car-cinoembryonic Antigen,CEA)是上皮性肿瘤的标记物。应用生化和免疫技术已证实它们不仅分布广泛,而且细胞角蛋白的种类和结构十分复杂,亚型多达19种。不同上皮性肿瘤,其细胞角蛋白的亚型和含量都不相同,因此选用抗不同亚型细胞角蛋白抗体可协助肿瘤的诊断,尤以对低(未)分化上皮性肿瘤的鉴别诊断。本文对膀胱癌细胞角蛋白和癌胚抗原进行观察,并对组织切片中二者的存在与膀胱癌病理分类分级上的联系报道如下。
Cytokeratin and Carcinoembryonic antigen (CEA) are markers of epithelial tumors. The application of biochemical and immunological techniques has proved that they are not only widely distributed, but also the type and structure of cytokeratin is very complicated, up to 19 subtypes. Different epithelial tumors, the cytokeratin subtypes and content are not the same, so the selection of different subtype of cytokeratin antibodies can help diagnose tumors, especially in the differential diagnosis of low (un) differentiated epithelial tumors. This article on the bladder cancer cytokeratin and carcinoembryonic antigen was observed, and the existence of both tissue sections and bladder cancer pathological classification of the grade of the report is reported below.