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分析许多药物制剂的生产工艺过程表明,脉动层干燥器可用于干燥温度不允许超过50～80℃的晶状制剂。如,所有四环素系列的抗生素和某些其它制剂。脉动层干燥器的特点是结构并不复杂。不过,为了保证最佳的干燥效果,当设计干燥器时必须选择最适宜的工作室结构形状和向工作室底部供给气体的设施。本文提出了确定脉动层干燥器工作室最佳几何参数的建议。在中间试验装置上(直径0.2m,高度0.7m,分离区域直径为0.4m)进行研究气体供
The analysis of the production process of many pharmaceutical formulations shows that the pulsation layer dryer can be used in crystalline formulations where the drying temperature is not allowed to exceed 50-80 ° C. For example, all tetracycline antibiotics and some other preparations. Pulsating layer dryer is characterized by the structure is not complicated. However, in order to ensure the best drying effect, when designing the dryer must choose the most appropriate studio structure and the bottom of the studio to provide gas facilities. This paper presents a suggestion to determine the best geometrical parameters of the pulsation layer drier studio. The gas supply was performed on an intermediate test device (diameter 0.2 m, height 0.7 m, separation area diameter 0.4 m)