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玻璃体积血(vitreous Hemorrhage,VH)是眼外伤及多种眼病的常见并发症,致盲率较高.为寻找对VH吸收疗效显著且使用方便的中药,我们曾用同位素~(51)Gr标记之RBC悬液注入兔眼内制成模型,采用虎杖及田七进行治疗,初步取得良好疗效.本试验对模型进行改进,进一步观察上述中药的疗效,同时对虎杖提取物结晶Ⅳ号及虎杖与田七合剂的疗效进行对比研究,对其药理机制进行初步探讨,现报道如下. 材料与方法一、疗效观察 (一)VH模型制作试验动物为新西兰白兔24只,雌雄兼用,体重2.0~3.5kg.首先对RBC进行标记:24只兔均由耳缘动脉
Vitreous Hemorrhage (VH) is a common complication of ocular trauma and various eye diseases, and has a high rate of blindness.In order to find a traditional Chinese medicine with significant therapeutic effect on VH absorption, we used isotope 51 Gr Of RBC suspension injected into the rabbit eye model, the treatment of Polygonum cuspidatum and Tianqi, initially achieved good results.In this study, the model was improved to further observe the curative effect of the above Chinese medicine, and Polygonum cuspidatum extract No. IV and Polygonum cuspidatum Seven mixture of the efficacy of comparative studies, the pharmacological mechanism of a preliminary study, are reported as follows.Materials and methods First, the efficacy of observation (A) VH modelThe experimental animal New Zealand white rabbits 24, both male and female, body weight 2.0 ~ 3.5kg RBCs were first labeled: 24 rabbits were all from the ear artery