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在一项新的研究中,来自英国剑桥大学韦尔科姆基金会桑格学院研究所和美国洛斯阿拉莫斯国家实验室的研究人员和他们的合作者测量了吸烟在人体不同器官中导致的灾难性遗传损伤,鉴定出吸烟导致DNA突变的几种不同机制。他们发现对每天吸一包烟的吸烟者而言,这些吸烟者的每个肺细胞每年积累着平均150个额外的突变。相关研究结果发表在Science期刊上。这项研究提供一生当中抽的香烟数量与人肿瘤DNA中的突变数量之间存在的直接关联性。最高的突变率是在肺癌中观察到的,但是人体
In a new study, researchers from the Sanger Institute, Cambridge, UK, and the Los Alamos National Laboratory at the University of Cambridge, UK, and their collaborators measured the effects of smoking on different organs of the human body Disastrous genetic damage identified several different mechanisms by which smoking causes DNA mutations. They found that for every smoker who smoked a pack of cigarettes a day, each smokers’ lung cells accumulated an average of 150 extra mutations per year. Relevant research results published in Science journals. This study provides a direct correlation between the number of cigarettes drawn during a lifetime and the number of mutations in human tumor DNA. The highest mutation rate is observed in lung cancer, but in humans