【摘 要】
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Wu and colleagues letter discusses the limitations of the use of a single sample per tumor to investigate neutral evolution in human cancers.Neutral tumor evolu
【机 构】
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Evolution and Cancer Laboratory, Barts Cancer Institute, Queen Marry University of London,London, UK
论文部分内容阅读
Wu and colleagues letter discusses the limitations of the use of a single sample per tumor to investigate neutral evolution in human cancers.Neutral tumor evolution describes the situation in which there is no differential clonal selection amongst the population of cells within a cancer:all mutations that accrue during growth are passengers and all drivers were already present in the most recent common ancestor of the population.
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