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目的探讨该地新生儿早产的可能危险因素,为新生儿早产的病因学研究提供科学依据。方法采用1∶2配对病例对照研究方法,选取2014年5月-11月期间在西安交通大学第一附属医院住院分娩的早产产妇130例和260名正常分娩产妇进行回顾性分析;采用单因素和多因素条件Logistic逐步回归进行新生儿早产危险因素分析。结果单因素χ2检验结果显示,从事体力劳动者、人工流产史、妊娠期高血压疾病、胎膜早破、前置胎盘、臀位与早产的发生有统计学关联(P<0.05)。多因素条件Logistic回归分析显示,从事体力劳动者(OR=2.572,95%CI:1.071~6.174)、妊娠期高血压疾病(OR=29.704,95%CI:10.805~81.655)、胎膜早破(OR=5.774,95%CI:2.814~11.845)、前置胎盘(OR=42.228,95%CI:9.509~187.522)、臀位(OR=5.462,95%CI:1.772~16.839)是新生儿早产的危险因素。结论早产的危险因素是多方面的,需采取综合的防治措施。
Objective To explore the possible risk factors of neonatal preterm birth in this area and provide a scientific basis for the etiological study of neonatal preterm birth. Methods The 1: 2 matched case-control study method was used to select 130 cases of preterm labor and 260 normal delivery women who were hospitalized and delivered in the First Affiliated Hospital of Xi’an Jiaotong University from May to November 2014. The single- Logistic stepwise regression analysis of risk factors for preterm birth in neonates. Results The results of the single factor χ2 test showed that the incidence of manual labor, history of abortion, hypertensive disorder of pregnancy, premature rupture of membranes, placenta previa, breech and preterm labor were statistically significant (P <0.05). Multivariate conditional Logistic regression analysis showed that those who engaged in manual labor (OR = 2.572,95% CI: 1.071 ~ 6.174), gestational hypertension (OR = 29.704,95% CI: 10.805 ~ 81.655), premature rupture of membranes OR = 5.774, 95% CI: 2.814-11.845), placenta previa (OR = 42.228, 95% CI: 9.509-187.522), breech position (OR = 5.462, 95% CI: 1.772-16.839) Risk factors. Conclusion There are many risk factors for preterm birth, and comprehensive prevention and treatment measures are needed.