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本实验观察了母牛分支杆菌菌苗对实验性尘肺大鼠防治结核病的作用。基本方法是:先用二氧化硅给大鼠染尘,两周后用母牛分支杆菌免疫,再经一个月后感染结核菌,染菌后一个半月解剖,观察母牛分支杆菌及异烟肼二者单用和并用对大鼠尘肺防治并发肺结核的效果,主要观察指标为肺脏中活菌单位数。结果:1 肺脏(1g)中活菌数(×10~4CFU)1 染尘染菌对照组——18.9±18.1;2 母牛分支杆菌免疫组——4.43±3.97;3 异烟肼给药
This experiment observed the role of Mycobacterium vaccae vaccine in prevention and treatment of tuberculosis in experimental pneumoconiosis rats. The basic method is: first with silica dust to rats, two weeks after the use of Mycobacterium vaccae immunization, and then infected with TB after a month, one and a half months after the bacteria dissection, observation of Mycobacterium cow and isoniazid Both alone and in combination with the effect of pneumoconiosis on pulmonary tuberculosis in rats, the main observation indicators for the number of viable cells in the lungs. 1 lung (1g) live bacteria (× 10 ~ 4CFU) 1 Dyeing and Dyeing bacteria control group - 18.9 ± 18.1; 2 Mycobacterium vaccae immunization group - 4.43 ± 3.97; 3 isoniazid