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心房颤动在老年人占有一定比例 ,房颤关联的脑中风是老年中突出的一个问题 ,非瓣膜房颤比其它原因导致的脑中风更严重、死亡率和致残率更高 ;大规模临床随机试验结果表明 ,抗凝治疗可明显降低房颤患者的缺血性脑中风发生率 ,使用华法林比阿司匹林预防缺血性脑中风效果更好 ,尤其是降低心源性栓塞中风 ;高龄患者是高危人群 ,应加强抗凝治疗 ,但抗凝强度应该是 :小剂量的、尽可能低的有效强度 ,国际标准化比率 (internationalnormalizedratio,INR)在 1 7~ 2 5范围更合适
Atrial fibrillation in the elderly occupy a certain percentage of stroke associated with stroke is a prominent issue in the elderly, non-valvular atrial fibrillation than other causes of stroke more severe, higher mortality and morbidity; large-scale clinical randomized The results show that anticoagulant therapy can significantly reduce the incidence of ischemic stroke in patients with atrial fibrillation, the use of warfarin than aspirin to prevent ischemic stroke is better, especially to reduce the cardioembolic stroke; elderly patients are Anticoagulation should be enhanced in high-risk populations, but anticoagulation should be: low-dose, as low as possible, with an international normalized ratio (INR) in the 17 to 25 range