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据美国医生报道,口服维生素B_(12)治疗恶性贫血是便宜而有效的方法。英国国家药方集(BNF)记载,由于口服维生素B_(12)有吸收不良的缺点,因此应用大大受限。这种观点在美国也普遍存在。因此,在英国治疗的首选是用羟钴铵注射剂,而在美国则选用氰钴铵注射剂。但据明尼苏达大学的一位医生报道,在瑞典有40％需要维生素B_(12)补充治疗的病人采用口服给药。据瑞典的研究,采用口服给药结果的成功率很高。
According to the U.S. doctors, oral administration of vitamin B_ (12) is a cheap and effective method of treating pernicious anemia. British National Formulary (BNF) records that due to the shortcomings of oral vitamin B_ (12) malabsorption, the application is greatly limited. This view is also widespread in the United States. Therefore, the first choice of treatment in the United Kingdom is to use hydroxycobalamin injection, while in the United States choose cyanocobalamin injection. However, a doctor at the University of Minnesota reported that 40% of patients in Sweden who require vitamin B_ (12) replacement therapy are given oral doses. According to Swedish studies, the success rate of oral administration results is high.