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在有效的治疗药物发现之前,急性白血病(AL)的预后恶劣,其自然病程,约为4个月。继各种有效抗白血病药物相继用于临床,特别是由于细胞动力学知识日益丰富和开展联合化疗以来,AL的缓解率显著提高,缓解期延长。不少国家或地区都有一批长期生存者的报告。目前儿童急性淋巴细胞型白血病(ALL)5年生存率已达到60%。本文在复习国外几组
The prognosis for acute leukemia (AL) is poor before the discovery of an effective therapeutic drug, with a natural course of about 4 months. Following a variety of effective anti-leukemia drugs have been used clinically, especially since the knowledge of cell-rich and increasingly extensive joint chemotherapy, AL remission rate was significantly improved, extended remission. Many countries or regions have a number of long-term survivors report. At present, the 5-year survival rate of childhood acute lymphoblastic leukemia (ALL) has reached 60%. This article reviews several foreign groups