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目的 探讨RP患者眼电图(EOG)的特征以及EOG作为评估RP手术疗效的客观指标的可能性。方法 采用MVT-3型视觉电生理仪的EOG采集和分析软件,对正常对照组和RP患者组在术前与术后进行检测。结果 (1)105名RP患者的EOG曲线大体可分为两种类型,即弯曲型与平坦型。弯曲型EOG各项参数较接近正常组EOG,该组绝大部分患者的视野马斑驳状;而平坦型EOG的一些主要参数(如Arden比和G比值等),明显地低于正常组,该组患者的视野多为管状视野或视野完全缺损。(2)在进行手术后半年以上复查EOG,则一些主要参数数值增加,有的患者(34.5％)的EOG由平坦型转变为弯曲型。结论 RP患者的EOG具有为该病所特有的特征,术后随主观症状的改善,EOG异常也恢复或部分恢复,这些都可作为该病诊断以及术后疗效评估的客观指标之一。
Objective To investigate the characteristics of electrooculography (EOG) in RP patients and the possibility of using EOG as an objective measure to assess the efficacy of RP surgery. Methods The EOG acquisition and analysis software of MVT-3 visual electrophysiology instrument was used to detect the patients in normal control group and RP patients before and after operation. Results (1) The EOG curves of 105 RP patients can be divided into two types: curved and flat. Curved EOG parameters closer to the normal group EOG, the vast majority of patients in the field of view horse mottled; flat EOG some of the major parameters (such as Arden ratio and G ratio, etc.), significantly lower than the normal group, Most patients in the field of vision of the tube or field of vision completely defect. (2) EOG was reviewed more than six months after surgery, some of the major parameters increased, and in some patients (34.5%) EOG changed from flat to curved. Conclusion EOG in patients with RP has the characteristics of this disease. With the improvement of subjective symptoms after surgery, the recovery of EOG abnormality or the partial recovery of EOG can be regarded as one of the objective indexes for the diagnosis and postoperative evaluation of EOG.