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目的:评价卡前列素氨丁三醇与缩宫素联用对产后出血的防治作用。方法:选取2012年9月—2015年3月收治的产后出血高危因素的产妇90例,按治疗方法的不同将其分为观察组和对照组(每组45例);对照组产妇给予缩宫素治疗,观察组产妇在对照组基础上加用卡前列素氨丁三醇治疗;比较两组产妇产后2 h和24 h出血量、血红蛋白值下降值和出血的发生率。结果:观察组产妇产后2 h和24 h出血量和血红蛋白下降值均明显低于对照组(P<0.05),出血的发生率为6.67%明显低于对照组为20.00%(P<0.05)。结论:采用卡前列素氨丁三醇与缩宫素治疗产后出血高危因素的产妇,其预防产后出血的发生效果较为明显。
OBJECTIVE: To evaluate the preventive and therapeutic effects of carboprost trometamol combined with oxytocin on postpartum hemorrhage. Methods: Totally 90 maternal women at risk of postpartum hemorrhage from September 2012 to March 2015 were divided into observation group and control group (45 cases in each group) according to different treatment methods; The treatment group and the observation group were treated with carboprost plus tromethamine on the basis of the control group. The blood loss, hemoglobin value and hemorrhage were compared between the two groups at 2 h and 24 h postpartum. Results: The amount of hemorrhage and hemoglobin drop in the observation group were significantly lower than those in the control group at 2 h and 24 h (P <0.05). The incidence of bleeding was 6.67% in the observation group, which was significantly lower than that in the control group (20.00%, P <0.05). CONCLUSION: The effect of using carboprost and oxytocin to treat the high risk factors of postpartum hemorrhage is more obvious in preventing postpartum hemorrhage.