北京儿童血清幽门螺杆菌抗体的检测价值

• 机 构: 电子工业部北京402医院
• 出 处: 华人消化杂志
• 发表日期: 1998年4期
• 关键词: HELICOBACTER PYLORI HELICOBACTER INFECTIONS ANTIBODIES BACTERIAL/ANALYSIS GASTRI

目的评价儿童血清HP?AB检测的价值,过筛儿童HP相关胃炎(HP?G).方法健康组为随机抽样北京市107例健康儿童,症状组为有上消化道症状的儿童122例.采用ELISA法测定血清HP?AB.对HP?AB阳性儿童随机纤维内镜检查(GF)及HPUT检查.结果健康组HP?AB阳性率为3?8％(4/107),症状组HP?AB阳性率为27?9％(34/122),经统计学处理有显著性差异(χ2＝23?98,P＜0?01).随机GF及HPUT检查阳性率92?9％,确诊为HP?G.结论HP是儿童胃炎的主要致病因素.北京健康儿童HP?AB阳性率近似西方发达国家.有上消化道症状儿童HP?AB阳性率高于健康儿童.HP?AB检测可以做为儿童HP?G筛查方法,对有HP感染症状儿童可以做为诊断方法“,”AIM To evaluate the detection of serum Hp Ab and to screen Hp associated gastritis (Hp G) in children. METHODS Serum Hp Ab of healthy group (107 healthy children from Beijing) and symptomatic group (122 children with symptom of upper gastrointestinal tract), were detected by ELISA, and then gastroscopy with HpUT was randomly performed in children with positive Hp Ab. RESULTS Hp Ab positive rate in the healthy group was 3 8%(4/107), and 27 8%(34/122) in symptomatic group, with a significant statis...