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作者在以前曾发现,实验性急性肠梗阻时,受损害的肠组织中,细胞的溶酶体释放出大量酸性水解酶,包括酸性磷酸酶和酸性核酸酶等,这些酶进入血液,对细胞膜有损害作用;在疾病早期加重器官的功能不全,以后可引起严重的器官实质的破坏性病变。作者检查急性肠梗阻38例(绞窄性23例,阻塞性15例)。在手术前、后检查病人血清酸性磷酸酶活性(氏法)和酸性核酸酶活性(紫外线吸收法);检查反映红细胞膜情况的下列指标:①、红细胞膜脂质过氧化物的氧化强度—测定红细胞培育前、后丙二酰二醛(过氧化物的氧化产物之
The authors have previously found that in experimental acute intestinal obstruction, the lysosomal lysate of cells releases a number of acidic hydrolases, including acid phosphatases and acid nucleases, which enter the bloodstream and damage the cell membrane Damaging effect; aggravating the organ dysfunction in the early stage of the disease, can cause serious organ devastating lesions later. The authors examined 38 cases of acute intestinal obstruction (strangulation in 23 cases, obstructive 15 cases). Preoperative and postoperative examination of patients with serum acid phosphatase activity (method) and acid nuclease activity (UV absorption method); check the following indicators reflect the erythrocyte membrane conditions: ①, erythrocyte membrane lipid peroxide oxidation intensity - determination Before and after erythrocyte incubation malondialdehyde (peroxide oxidation products