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选择138例血糖控制不良的糖尿病住院患者,给与胰岛素泵强化治疗,疗程5～8天,不合用其他口服降糖药。结果:血糖达满意控制的平均天数为5.2±1.7天,胰岛素泵的日基础量为0.22±0.09U/kg,早午晚餐前大剂量分别为0.12±0.06 U/kg,0.13±0.07 U/kg,0.12±0.05 U/kg,在血糖满意控制后,胰岛素量显著减少。发生低血糖症0.03±0.17(次/人),生化低血糖0.06±0.23(次/人),低血糖反应0.86±0.09(次/人)。结论:经过胰岛素泵的强化治疗,高血糖可在5～6天得以纠正,影响达目标血糖时间的因素为FPG和年龄,影响胰岛素用量的因素为糖尿病的病程、治疗前FPG和2hPG。
Select 138 patients with poor blood glucose control inpatients with diabetes, given insulin pump intensive treatment, treatment of 5 to 8 days, do not use other oral hypoglycemic agents. Results: The average number of days for satisfactory blood glucose control was 5.2 ± 1.7 days. The daily basal amount of insulin pump was 0.22 ± 0.09 U / kg and the high dose before breakfast, lunch and dinner was 0.12 ± 0.06 U / kg and 0.13 ± 0.07 U / kg, respectively , 0.12 ± 0.05 U / kg, a significant reduction in the amount of insulin after blood glucose was satisfactorily controlled. Hypoglycemia 0.03 ± 0.17 (times / person), biochemical hypoglycemia 0.06 ± 0.23 (times / person), hypoglycemia response 0.86 ± 0.09 (times / person). Conclusion: After intensive insulin treatment, hyperglycemia can be corrected within 5 to 6 days. The factors influencing the target blood glucose time are FPG and age. The factors influencing insulin dosage are the duration of diabetes, pre-treatment FPG and 2-hPG.