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目的 :探讨膀胱副神经节瘤的临床病理特点和鉴别诊断。方法 :通过HE及免疫组化染色观察 3例膀胱副神经节瘤并复习文献。结果 :膀胱副神经节瘤好发于年轻女性 ,常表现血尿 ,头痛 ,心悸 ,多汗 ,排尿后血压一过性升高。镜下似肾上腺嗜铬细胞瘤。 2例免疫组化示CgA ,NSE ,S - 10 0蛋白阳性 ,CK阴性。结论 :膀胱副神经节瘤为潜在恶性肿瘤 ,以膀胱部分切除为主。诊断需结合临床 ,病理及免疫组化结果。有条件者应长期随访
Objective: To investigate the clinicopathological features and differential diagnosis of paragangliomas. Methods: Three cases of paraganglioma of the bladder were observed by HE and immunohistochemistry, and the literature was reviewed. Results: Bladder paraganglioma occurs frequently in young women. Hematuria often presents with hematuria, headache, palpitation, hyperhidrosis and transient increase of blood pressure after urination. Microscopic adrenal pheochromocytoma. Two cases of immunohistochemistry showed CgA, NSE, S - 100 protein positive, CK negative. Conclusions: Paraganglioma is a potential malignant tumor with partial resection of the bladder. Diagnosis should be combined with clinical, pathological and immunohistochemical results. Conditions should be long-term follow-up