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癌症病人常伴有碳水化合物和脂肪代谢失常,而且整体蛋白质周转增快,骨骼肌蛋白质净平衡下降、丢失量也特别明显,所以大手术尤其是消瘦者,围术期病态和并发症增多,死亡率也上升。虽然这类病人一入院就积极静脉高营养,但也未必改善。作者曾给正常人使用生长激素重组合体(Recombinant growthhormone,简称r-hGH)三天,接着强制性处于正常血糖但高胰岛素血症状态,结果能改善机体动态蛋白质代谢。为此,作者选择28例癌症病人作类似研究。随机选12例为r-hGH组,16例为对照组。两组病人的年龄、身高、体重、占标准体重%(%IBW)、根据皮肤褶厚度计算出无脂肪身体质量(FFM)以及肌酸酐/身
Cancer patients are often accompanied by carbohydrate and fat metabolism disorders, and the overall protein turnover faster, skeletal muscle protein net balance decreased, the loss is also particularly evident, so major surgery, especially weight loss, perioperative morbidity and complications increased, death The rate also goes up. Although these patients are admitted to the hospital on the positive intravenous nutrition, but it may not improve. The authors have used normal human recombinant recombinant growth hormone (Recombinant Growth Hormone, r-hGH for three days, then forced to normal blood glucose but hyperinsulinemia, the results can improve the body’s dynamic protein metabolism. To this end, the author chose 28 cases of cancer patients for a similar study. 12 cases were randomly selected as r-hGH group and 16 as control group. Age, height, weight, standard weight% (% IBW), calculated body fat free mass (FFM), and creatinine /