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肿瘤的发生发展与免疫状态密切相关,T辅助淋巴细胞(Th)与T抑制淋巴细胞(Ts)是免疫反应的调节细胞,某些自身免疫疾病,免疫缺陷疾病,肿瘤等患者,Th、Ts比例常有显著的改变。目前认为T细胞功能状况取决于T细胞亚群的分布,Th/Ts比值可作为T淋巴细胞功能的参数。因此对T淋巴细胞亚群测定和分析对上述疾病的研究有一定的价值,本文应用OKT单克隆抗体(McAb)检测NPC患者外周血T淋巴细胞亚群,旨在了解患者的免疫状况及其在诊断上的意义,现将结果报道如下。 材 料 与 方 法 一、检测对象:15例NPC患者均为中山医科大学附属肿瘤医院鼻咽癌病区,经活检病理确诊,治疗前的住院病人,男11例,女4例,年龄26～64岁(平均44岁)。正常对照组20人,均为本单位健康职工,男8人、女12人,年龄20～58岁(平均40岁)。
The occurrence and development of tumors are closely related to the immune status. T-helper lymphocytes (Th) and T-suppressor lymphocytes (Ts) are regulatory cells of immune response. In some patients with autoimmune diseases, immunodeficiency diseases and tumors, the Th and Ts ratio Often there are significant changes. It is currently believed that T cell function depends on the distribution of T cell subsets, Th / Ts ratio can be used as T lymphocyte function parameters. Therefore, T lymphocyte subsets measurement and analysis of the above diseases have some value in this study, the OKT monoclonal antibody (McAb) detection of peripheral blood T lymphocytes in patients with NPC, aimed at understanding the patient’s immune status and its Diagnostic significance, the results are reported below. Materials and Methods First, the test object: 15 cases of NPC patients were nasopharyngeal cancer patients affiliated with Cancer Hospital of Sun Yat-sen University, biopsy pathology confirmed before treatment, 11 males and 4 females, aged 26 to 64 years (Average 44 years old). The normal control group of 20 people, are the units of health workers, 8 males and 12 females, aged 20 to 58 years (mean 40 years).