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目的:观察无创正压通气(NIPPV)治疗慢性阻塞性肺疾病(COPD)合并肺性脑病的效果。方法:选择我院收治的COPD合并肺性脑病92例,随机分为观察组和对照组各46例。观察组采用双水平NIPPV治疗,对照组采用气管插管有创通气治疗;对比观察评价两组通气治疗时间、住院天数及病死率。结果:观察组通气治疗时间(8.6±4.3)天,显著短于对照组的(15.2±5.7)天(P<0.05);观察组住院时间(15.0±5.3)天,显著短于对照组的(22.6±2.8)天(P<0.05);观察组病死率为30.7%,与对照组的35.0%比较差异不显著(P>0.05)。结论:NIPPV治疗COPD)合并肺性脑病效果确切。
Objective: To observe the effect of noninvasive positive pressure ventilation (NIPPV) on chronic obstructive pulmonary disease (COPD) with pulmonary encephalopathy. Methods: A total of 92 COPD patients with pulmonary encephalopathy admitted to our hospital were randomly divided into observation group (46 cases) and control group (46 cases). The observation group was treated with double-level NIPPV, while the control group was treated with tracheal intubation with invasive ventilation. The duration of ventilation, hospital stay and mortality were compared between the two groups. Results: The duration of ventilatory treatment in the observation group was (8.6 ± 4.3) days, which was significantly shorter than that in the control group (15.2 ± 5.7) days (15.0 ± 5.3), significantly shorter than that in the control group 22.6 ± 2.8) days (P <0.05). The case fatality rate in the observation group was 30.7%, which was not significantly different from that in the control group (35.0%) (P> 0.05). Conclusion: NIPPV treatment of COPD with pulmonary encephalopathy with the exact effect.