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研究对象为61名妇女,平均年龄36±7.3岁,至少6个月内无激素治疗史或妊娠史。剖腹手术中取异位灶标本,其中54名同时诊刮取子宫内膜。原发和复发各占45和16例,共有标本69个。子宫内膜瘤、卵巢和腹腔异位灶标本中属复发的各占6/34(18％)、10/27(37％)和4/5(80％)。有8例分别取两个不同部位异位灶标本。应用免疫化学及配体技术测定ER和PR浓度,并以DNA(mg)含量来计算。已知末次月经史的58名妇女,分别于增生期(29名)、分泌期(26名)和月经期(3名)采集标本。结果异位组织中ER和PR浓度、原发异位灶中胞质ER浓度,都明显低于子宫内膜中相
The study population was 61 women with an average age of 36 ± 7.3 years and no history of hormone therapy or pregnancy within at least 6 months. Laparotomy surgery to take heterotopic specimens, of which 54 simultaneous diagnosis of endometrial scraping. There were 45 and 16 primary and recurrent cases respectively, with a total of 69 specimens. There were 6/34 (18%), 10/27 (37%) and 4/5 (80%) patients with endometrial, ovarian and peritoneal ectopic respectively. There are 8 cases were taken two different parts of ectopic focus specimens. The concentrations of ER and PR were determined using immunochemical and ligand techniques and calculated as DNA (mg) content. Fifty-eight women with the last menstrual history were collected in the proliferative phase (29), secretory phase (26) and menstrual period (3). Results The concentration of ER and PR in ectopic tissues and the concentration of cytoplasmic ER in primary ectopic lesions were significantly lower than those in the endometrium