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卡托普利(CPT)是一种常用的血管紧张素转换酶抑制剂,自1977年问世以来,已广泛用于临床,特别在充血性心力衰竭和高血压病的治疗上开辟了新的用途。但随着临床应用的日益广泛,其不良反应报告也日渐增多,尤其CPT引起干咳的报告较多,发生率在1.3%—30%不等。女性多于男性。多为刺激性干咳,常在夜间加剧,甚至达到尿失禁程度。通常于用药后几日发病,也有长至数月才开始发作。一般停药后可明显减轻或消失,但再用CPT时又可出现咳嗽复发。我院1994年5
Captopril (CPT), a commonly used angiotensin-converting enzyme inhibitor, has been widely used clinically since 1977 and has opened up new uses especially for the treatment of congestive heart failure and hypertension . However, with the increasingly wide range of clinical applications, its adverse reaction reports are also increasing, especially in CPT caused more reports of dry cough, the incidence of 1.3% -30%. More women than men. Mostly irritating dry cough, often intensified at night, and even reached the level of urinary incontinence. Usually a few days after the onset of medication, but also as long as a few months before the onset. After the general withdrawal may be significantly reduced or disappeared, but when re-use of CPT cough relapse. Our hospital in 1994 5