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调查了９８名铬接触工人，发现尿γ－ＧＴ活性与工龄和尿铬呈明显平行关系，另外与尿蛋白和尿β２－ＭＧ呈显著正相关（Ｐ＜０．０１）。当受检者尿蛋白和尿β２－ＭＧ均正常时，尿γ－ＧＴ已显著高于对照组，并随肾损害程度加重而明显增加。但尿ＮＡＧ仅在尿β２－ＭＧ和尿蛋白均异常时显著高于对照组；尿ＮＡＧ与尿蛋白呈显著正相关（Ｐ＜０．０５）。这提示尿γ－ＧＴ可作为铬性肾损害较灵敏的早期检测指标，结合尿ＮＡＧ水平可初步判断铬性肾损害的程度。
A survey of 98 workers exposed to chromium revealed a clear parallel relationship between urine γ-GT activity and length of service and urine chromium, and a significant positive correlation (P <0.01) with urine protein and urine β2-MG. Urine γ-GT was significantly higher than that of the control group when urinary protein and urinary β2-MG levels were normal, and significantly increased with the degree of renal damage. However, urinary NAG was significantly higher than that of the control group only when urinary β2-MG and urinary protein were abnormal. Urinary NAG was positively correlated with urinary protein (P <0.05). This suggests that urine γ-GT can be used as a more sensitive early detection of chromium nephrosclerosis indicators, combined with urinary NAG levels can be a preliminary assessment of the extent of chronically kidney damage.