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近年来,对失去手术机会的晚期胃癌仍然采用放疗、化疗药物治疗,但常规剂量难以取得满意疗效,而大剂量使用副作用又大,使临床应用受到限制。据报道,黄芪具有抗氧化作用。可以增强荷瘤动物细胞免疫功能及有抑制肿瘤生长的作用。为此,我们采用以黄芪为主药的补阳还五汤加减,治疗晚期原发性胃癌96例,现报道如下。1 临床资料1.1 一般资料 全部资料选择经病理确诊的晚期胃癌患者,均因各种原因失去手术机会(胃、脑、肾、肝转移,肝肾功能及心电图异常者不列入观察范围)。患者分为治疗组96例(中药煎剂加服复方氟尿嘧啶片)和对照组(单纯服复方氟尿嘧啶片)92例。
In recent years, radiotherapy and chemotherapeutic drugs have been used to treat advanced gastric cancers that have lost the chance of surgery. However, it is difficult to achieve satisfactory results with conventional doses, and large doses have large side effects, which limits clinical applications. According to reports, Astragalus has antioxidant effects. It can enhance the cellular immune function of tumor-bearing animals and inhibit the growth of tumors. To this end, we use the treatment of Buyang Huanwu Decoction, which is mainly based on astragalus, to treat 96 cases of advanced primary gastric cancer. The report is as follows. 1 Clinical data 1.1 General information All data selected by pathologically confirmed patients with advanced gastric cancer, are lost due to various reasons for surgery (stomach, brain, kidney, liver metastases, liver and kidney function and ECG abnormalities are not included in the scope of observation). The patients were divided into a treatment group of 96 patients (Chinese herbal decoction plus compound fluorouracil tablets) and a control group (simple medication fluorouracil tablets) 92 patients.