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大量研究表明,宫颈癌的发病与性传播的病毒有关。起初认为,HSV 可能是病原体,但以后的观察提示 HSV 在肿瘤形成过程中只起辅助因子的作用。另一研究表明 HPV 也参与宫颈癌的致病。普遍认为恶性肿瘤的发生和发展是一个多种致癌因素相互作用的循序渐进的过程。HSV-2作为诱变剂,在宫颈癌致病中起辅助 HPV 的作用。本文作者用免疫组织化学技术,对宫颈非典型增生,宫颈癌和正常对照妇女的宫颈活检进行检测,显示 HSV-2和HPV 抗原同时存在。材料和方法:选择96例经组织学确诊为不
Numerous studies show that the incidence of cervical cancer and sexually transmitted viruses. At first thought, HSV may be the pathogen, but later observations suggest that HSV only plays a role as a cofactor in tumorigenesis. Another study shows that HPV is also involved in the pathogenesis of cervical cancer. It is generally believed that the occurrence and development of malignant tumors is a gradual process of the interaction of many carcinogenic factors. HSV-2 as a mutagen in the pathogenesis of cervical cancer plays a role in assisting HPV. The authors used immunohistochemical techniques to detect cervical atypical hyperplasia, cervical cancer and normal control women’s cervical biopsy, HSV-2 and HPV antigens exist. Materials and Methods: 96 cases were selected as histologically diagnosed as no