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目的分析三维适形放疗联合同期化疗治疗中晚期食管癌的毒副反应与临床疗效。方法 148例中晚期食管癌患者,随机分为观察组和对照组,各74例。对照组实施单纯三维适形放疗,观察组在此基础上实施同期化疗。比较两组患者的治疗效果。结果观察组患者在治疗效果以及1年生存率均明显高于对照组(P<0.05)。两组患者毒副反应发生率比较差异无统计学意义(P>0.05)。结论采用三维适形放疗联合同期化疗的方法对中晚期食管癌患者进行治疗能够明显提升临床治疗效果,毒副反应通过积极对症治疗患者可耐受,对患者有重要意义,应用价值高,值得推广使用。
Objective To analyze the toxic side effects and clinical effects of three-dimensional conformal radiotherapy combined with concurrent chemotherapy in the treatment of advanced esophageal cancer. Methods 148 cases of advanced esophageal cancer patients were randomly divided into observation group and control group, 74 cases in each. The control group was treated with simple three-dimensional conformal radiotherapy, while the observation group was treated with concurrent chemotherapy. The treatment effect of two groups of patients was compared. Results The therapeutic effect and 1-year survival rate of the observation group were significantly higher than those of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Three-dimensional conformal radiotherapy combined with concurrent chemotherapy for patients with advanced esophageal cancer treatment can significantly improve the clinical effect of treatment, toxic side effects through the positive symptomatic treatment of patients with tolerance, is of great significance to patients with high value, it is worth promoting use.