论文部分内容阅读
Following peripheral nerve injury,distal and proximal fibers undergo a series of changes in cell and molecular biology that can result in hypoesthesia,neuropathic pain,loss of motor function and muscle atrophy in the target area.Nerve injury treatment and subsequent regeneration and functional recovery are historical clinical problems.Currently,studies concing peripheral nerve repair mainly focus on anastomosis,nerve grafting and bridging nerve defects.However,the effect of repair is insufficient and unsatisfactory;it is reported that after surgery,original functionality is recovered in only approximately 10％ of patients.The largest difference between nerve tissue repair and other tissue repair is that nerve tissue cannot be replaced by scar tissue,and can only be restored by self-repair.