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目的 探讨两种病原体引起的中枢神经系统感染的临床特征 ,评估神经影像学在鉴别诊断中的作用。方法 回顾性对比分析两种脑膜炎的主要临床表现、脑脊液变化、头颅CT或MRI改变。结果 新型隐球菌性脑膜炎起病迁延 ,首发症状至住院诊治有更长间期 ,头痛伴有呕吐 ,视乳头水肿伴有出血 ,脑脊液压力高伴有葡萄糖含量明显减低。结核性脑膜炎急性或亚急性发病 ,腱反射减低或消失 ,脑脊液细胞数增多。两种脑膜炎有着各自神经影像学特征。结论 神经影像学异常提供和补充了诊断和鉴别诊断的重要信息
Objective To investigate the clinical characteristics of central nervous system infection caused by two pathogens and to evaluate the role of neuroimaging in differential diagnosis. Methods The clinical manifestations, cerebrospinal fluid changes, CT or MRI changes of two kinds of meningitis were retrospectively analyzed. Results Cryptococcus neoformans meningitis onset delayed, the first symptom to hospitalization for a longer period of time, headache associated with vomiting, papilledema with bleeding, high cerebrospinal fluid pressure associated with significantly reduced glucose content. Acute or subacute tuberculous meningitis incidence, reduce or disappear tendon reflex, increased cerebrospinal fluid cells. Both meningitis have their own neuroimaging features. Conclusion Neuroimaging abnormalities provide and supplement important information for diagnosis and differential diagnosis