早产儿动脉导管未闭的危险因素

• 作 者: 燕旭东 吴本清
• 机 构: 暨南大学第二附属医院深圳市人民医院新生儿科,
• 出 处: 医学综述
• 发表日期: 2012年05期
• 关键词: 早产儿 后遗症发生率 慢性肺疾病 动脉导管未闭 早产儿死亡率 组织形态学 呼吸窘迫 体质量 危险因素 颅内出血

动脉导管未闭(PDA)是早产儿常见的并发症之一,可导致或加重呼吸窘迫、慢性肺疾病、颅内出血和坏死性小肠结肠炎的发生发展,它的存在与早产儿死亡率和后遗症发生率提高密切相关。早产儿发生PDA与多种因素有关,包括因胎龄及出生体质量所致的组织形态学和病理生理学上的因素、产科因素、其他并发症、遗传、环境因素等。对其危险因素进行综述有助于提高对该疾病的认识。

Patent ductus arteriosus (PDA) is one of the most common complications of premature infants, which can lead to or aggravate the development of respiratory distress, chronic lung disease, intracranial hemorrhage and necrotizing enterocolitis. It is associated with premature infant mortality and sequelae The incidence is closely related. PDA occurs in preterm infants and a variety of factors, including due to gestational age and birth weight due to histological and pathophysiological factors, obstetric factors, other complications, genetic, environmental factors. A review of their risk factors can help raise awareness of the disease.