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丝虫病是我国农村常见病、多发病之一。我国用海群生治疗丝虫病自1948年开始至今近30年。但由于其治疗效果并不十分理想,且在治疗过程中引起一些治疗反应,特别对马来丝虫病的反应更大,为普治带来很大困难,直接影响送走丝虫这个“瘟神”的进程。为寻找抗丝虫的新药,近年来国内、外用感染了棉鼠丝虫(Litomosoides carinil)和魏氏盖头丝虫(Dipetalonema viteae)的长爪沙鼠(Meriones unguiculatus)(Striebel,1976)及感染了棉鼠丝虫的棉鼠(Sigmodon hispidus)(上海寄生虫病研究所,1975)进行抗丝虫药物筛选的实验研究。我组于1977年利用人工感染了周期型马来丝虫的长爪沙鼠对
Filariasis is one of the most common and frequently occurring diseases in rural areas of China. In China, the endemic filariasis has been treated by sea for nearly 30 years since 1948. However, due to its therapeutic effect is not very satisfactory, and in the course of treatment caused some treatment response, especially greater response to Malayan filariasis, brought great difficulties for Purcell, directly affect the transmission of filariasis “ ”Process. In order to find a new drug against filariasis, Meriones unguiculatus (Striebel, 1976) infected with Litomosoides carinil and Dipetalonema viteae, Sigmperton hispidus (Shanghai Institute of Parasitic Diseases, 1975) was used to screen antifungi drugs. My team in 1977 by artificial infection of the cycle of malayian worm gerbil pair